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diagnosis hematology differential oncology causes management mentzerindex myelodysplasia myelodysplastic rdw reticulocytes syndromes thrombocytes
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... with Pancytopenia ... • Toxins • Aplastic ... Anemia • Myelodysplasia ... deficiency: • B12
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Differential Diagnosis Algorithm ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Differential Diagnosis Algorithm ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... bone marrow + pancytopenia ... Difficulty breathing • Neutropenia ... • Peripheral Pancytopenia
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Pancytopenia is ... hemoglobin of less than 12 ... primarily seen as neutropenia ... Satyendra Dhar MD
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Aplastic Anemia ... Myeloproliferative Disease • Neutropenia ... Nutritional: vitamin B12 ... Workup: • Complete
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