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diagnosis anemia aplastic causes chronic differential emergencies hemeonc lymphocytic management mds mentzerindex myelodysplasia myelodysplastic oncologic rdw reticulocytes syndromes thrombocytes
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... with Pancytopenia ... Myelofibrosis Stem cell ... deficiency: • B12 ... #Diagnosis #Algorithm
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
incompetent • CLL ... Cytopenias: • Neutropenia ... leukemia #CLL ... #diagnosis #workup ... #oncology #hematology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Pancytopenia is ... a hematologic condition ... hemoglobin of less than 12 ... primarily seen as neutropenia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
bone marrow + pancytopenia ... Difficulty breathing • Neutropenia ... virus (EBV) • Leukemia ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease • Neutropenia ... Nutritional: vitamin B12 ... Syndromes #diagnosis #hematology ... #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Emergencies Neutropenic ... full infectious work-up ... days → add fungal work-up ... syndrome): - Hematologic ... Usually myeloid leukemias
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