12 results
Causes of Vitamin B12 Deficiency - Cobalamin
Decreased Intake
Pancreas: Insufficiency
Intestine: SIBO, Celiac disease, IBD, Lymphoma, Amyloidosis, Resection,
Causes of Vitamin ... B12 Deficiency ... Stomach: Pernicious anemia ... #Deficiency #Cobalamin ... #differential #
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
red blood cell; MMA ... the most likely cause ... deficiency. ... #VitaminB12 #Folate ... #FolicAcid #MMA
Causes of Low Vitamin B12 Levels
Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people
Autoimmune
Causes of Low Vitamin ... B12 Levels Low ... vitamin B12 intake ... antagonists #VitaminB12 ... #cobalamin #differential
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... (>100 fL) • B12 ... #MCV #Classification ... #Differential #
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... ) Deficiency Etiology ... • Common Causes ... - Elevated MMA ... #Cobalamin #Deficiency
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... • B12/Folate ... Deficiency • Aplastic ... #Classification ... Diagnosis #Algorithm #Causes
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
Crohn's > UC Anemia ... Receptor (sTfR) to differentiate ... (B12, MMA) for ... restricted diet/deficiency ... /other causes
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
Whipple, vitamin deficiency ... Alzheimer - 1st cause ... - Progressive amnesia ... MNCD #Dementia #Differential ... #Subtypes #Classification
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... leakage of RBC's secondary ... - Hemolytic anemia ... necrosis) • VIT K deficiency ... GPA - EGPA - MPA
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... areas (less than 2 mm ... in primary or secondary ... Work Up: •