7 results
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
with Pancytopenia ... - Differential ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional deficiency ... : • B12/folate
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
Whipple, vitamin deficiency ... Alzheimer - 1st cause ... - Progressive amnesia ... #Dementia #Differential ... #Subtypes #Classification
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... (>100 fL) • B12 ... #MCV #Classification ... #Differential #
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... • B12/Folate ... Deficiency • Aplastic ... #Classification ... Diagnosis #Algorithm #Causes
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
bone marrow + pancytopenia ... and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... propylthiouracil) - β-lactam
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... malignancy, or thiamine deficiency ... 30mmHg) - Severe anemia ... effect - Thiamine deficiency ... #typea #typeb #classification
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Nutritional: vitamin B12 ... or folic acid deficiency ... Workup: • Complete ... blood count with differential