12 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Volume (MCV) - Differential ... • Drugs Oval Macrocytes ... • Dietary Deficiency ... #Anemia #Macrocytosis
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
evaluation of macrocytic ... the most likely cause ... deficiency. ... #Macrocytic #Anemia ... Algorithm #Workup #AAFP
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
" • Iron deficiency ... MCV - >96fL - "Macrocytic ... Megaloblastic: Vitamin B12 ... morphologic #mcv #differential ... #diagnosis #causes
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... Volume (MCV) - Differential ... RBC>13 • Iron Deficiency ... #Microcytic #Anemia ... #Macrocytosis #
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
Crohn's > UC Anemia ... If persistent macrocytosis ... Receptor (sTfR) to differentiate ... restricted diet/deficiency ... /other causes
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... : • Worsening macrocytic ... hypersegmented neutrophils, macrocytosis ... #Cobalamin #Deficiency
Causes of Wide Pulse Pressure - Differential Diagnosis
Physiologic:
 • Advanced age-arteriosclerosis (less compliant arteries)
 • Well
Causes of Wide Pulse ... Pressure - Differential ... - Severe iron deficiency ... fistula - Such as ... #cardiology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
common cytopenia: Macrocytic ... Nutritional: vitamin B12 ... or folic acid deficiency ... treatments • Copper deficiency ... blood count with differential
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Pulse Pressure - Differential ... Physiologic Causes ... • Severe iron deficiency ... anemia (reduced ... #cardiology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... malignancy, or thiamine deficiency ... 30mmHg) - Severe anemia ... effect - Thiamine deficiency ... Acidosis #Elevation #Differential