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diagnosis algorithm hematology causes management cobalamin elevatedmcv fatigue folate folicacid hemolysis homocysteine ibd mds myelodysplasia myelodysplastic nutrition oncology pathophysiology pressure
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
evaluation of macrocytic ... red blood cell; MMA ... deficiency. ... #Macrocytic #Anemia ... Algorithm #Workup #AAFP
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... • Drugs Oval Macrocytes ... • Dietary Deficiency ... and Folate Deficiency ... #Anemia #Macrocytosis
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... formerly known as ... crisis • Severe B12 ... deficiency • Mechanical ... macroangiopathic hemolytic anemia
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
Crohn's > UC Anemia ... If persistent macrocytosis ... Receptor (sTfR) to differentiate ... (B12, MMA) for ... restricted diet/deficiency
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... : • Worsening macrocytic ... hypersegmented neutrophils, macrocytosis ... - Elevated MMA ... #Cobalamin #Deficiency
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology Pulse pressure is the difference between the systolic blood
Pulse Pressure - Differential ... >100 mm Hg although ... • Severe iron deficiency ... anemia (reduced ... Pathophysiology #causes #cardiology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
common cytopenia: Macrocytic ... Nutritional: vitamin B12 ... or folic acid deficiency ... treatments • Copper deficiency ... blood count with differential
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