5 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... • Drugs Oval Macrocytes ... Neutrophils - Low RBC ... RBCs in Rouleaux ... #Anemia #Macrocytosis
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
evaluation of macrocytic ... (RBC = red blood ... B12 deficiency ... #Macrocytic #Anemia ... Algorithm #Workup #AAFP
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
) Morphology Microcytic ... , Iron deficiency ... (sometimes) Macrocytic ... RBC: Vitamin B12 ... #Morphology #differential
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... ) Deficiency Etiology ... : • Worsening macrocytic ... • Labs: - CBC ... hypersegmented neutrophils, macrocytosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
common cytopenia: Macrocytic ... • Nutritional: vitamin ... B12 or folic acid ... deficiency • Exposure ... blood count with differential