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diagnosis management algorithm cobalamin hematology aafp altered crrt fatigue folate folicacid homocysteine macrocytosis managment mcv mds mental mma modalities modes
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
evaluation of macrocytic ... the most likely cause ... recovery also causes ... B12 deficiency ... deficiency.
Causes of Vitamin B12 Deficiency - Cobalamin Decreased Intake Pancreas: Insufficiency Intestine: SIBO, Celiac disease, IBD, Lymphoma, Amyloidosis, Resection,
Causes of Vitamin ... B12 Deficiency ... Celiac disease, IBD ... Stomach: Pernicious anemia ... #B12 #Deficiency
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
MCV - >96fL - "Macrocytic ... Megaloblastic: Vitamin ... B12 deficiency, ... morphologic #mcv #differential ... #diagnosis #causes
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... ) Deficiency Etiology ... • Common Causes ... : • Worsening macrocytic ... diarrhea related to IBD
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
Crohn's > UC Anemia ... Receptor (sTfR) to differentiate ... restricted diet/deficiency ... report dehydration as ... /other causes •
Altered Mental Status - Differential Diagnosis • Neurologic: Stroke, Cerebral hypoxia, Cerebral hemorrhage, Seizure, Trauma, TBI,
Diagnosis • Neurologic ... , Hypercarbia, Vitamin ... deficiency, Thyroid ... Mental #Status #AMS ... Diagnosis #Causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... common cytopenia: Macrocytic ... • Nutritional: vitamin ... B12 or folic acid ... blood count with differential
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
B12 and copper ... • Nutritional Deficiency ... : - Vitamin B12 ... diagnosis #management #neurology ... #differential
Renal Replacement Therapy (RRT) - ICU One Pager Summary Indications (AIEOU): • A: Acidosis (usually severe metabolic)
Dialyzer is rigid case ... in the ICU: • IHD ... (Sustained low efficiency ... daily dialysis): ~12 ... RRT #managment #nephrology
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