8 results
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Pancytopenia - Differential ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • ... B12/folate/combined
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
• Fanconi’s anemia ... Autoimmune Diseases: • Systemic ... Antibody-mediated hemolysis Nutritional ... consumption • Vitamin B12 ... #Diagnosis #Hematology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
• Metabolic / Nutritional ... : DiabetesB12 deficiency ... , Uremia/ESRD, Hypothyroidism ... Peripheral #Neuropathy #differential ... diagnosis #causes #neurology
Etiologies of Vitamin B12 Deficiency
 • Inadequate intake - Rare but seen in very strict vegans
deficiency. ... autoantibodies (pernicious anemia ... #differential # ... diagnosis #hematology ... #nutrition
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... central nervous system ... endocrine: Vitamin B12 ... deficiency • ... #Diagnosis #neurology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Platelet Disorders • Nutritional ... : vitamin B12 or ... folic acid deficiency ... blood count with differential ... Syndromes #diagnosis #hematology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
antibodies • Nutritional ... Deficiency: - ... Vitamin B12, E, ... diagnosis #management #neurology ... #differential
Management of Pruritus in Patients with Chronic Kidney Disease
Pruritus with no primary lesions - differential diagnosis:
primary lesions - differential ... pruritus • Hematologic ... pruritus (Iron deficiency ... anemia, Polycythemia ... #Management #Nephrology