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differential management symptoms algorithm hematology classification cord geriatrics oncology pathophysiology spinal spinalcord syndromes acidosis alkaline alp aplastic arteritis ascorbicacid behcet
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... gestation • Vitamin B12 ... #differential #diagnosis ... #signs #symptoms ... #nutrition
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • ... B12/folate/combined
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... #Cobalamin #Deficiency ... #nutrition
Etiologies of Peripheral Neuropathy • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism • Medication-induced: ART, Antibiotics,
• Metabolic / Nutritional ... : DiabetesB12 deficiency ... , Uremia/ESRD, Hypothyroidism ... #differential #diagnosis ... #causes #neurology
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
fatigue despite clinical ... Crohn's > UC Anemia ... restricted diet/deficiency ... /other causes • ... IBD #Algorithm #diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... oncology #hematology #diagnosis
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... Most cases diagnosed ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
Scurvy (Vitamin C Deficiency ... ) - Diagnosis and ... Clinical Presentation ... Loss of teeth Anemia ... , or any other cause
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
workup 1) Clinical ... Whipple, vitamin deficiency ... Alzheimer - 1st cause ... - Progressive amnesia ... (parkinsonian signs
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... systemic sx + signs ... systemic complaints- anemia ... GCA #Temporal #Signs
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