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diagnosis differential hematology management algorithm aplastic chronic classification cll cord dementia geriatrics hypertension indications leukemia lymphocytic mds mncd myelitis myelodysplasia
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... - Coagulation disorder ... Wernicke-Korsakoff syndrome ... differential #diagnosis #signs
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
neurocognitive disorders ... 1) Clinical ... Whipple, vitamin deficiency ... Aphaso-apraxo-agnosia syndrome ... (parkinsonian signs
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Nutritional: vitamin B12 ... Workup: • Complete ... diagnosis #hematology #oncology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension - Workup ... hypertension and signs ... 109 mm Hg) with clinical ... renal bruit or signs ... Neurologic disorders
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Non-neuromuscular disorder ... endocrine: Vitamin B12 ... deficiency • ... Lack of UMN/LMN signs ... dystrophies Work
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... lymphoproliferative disorders ... • Neutropenia, anemia ... #oncology #hematology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... and pernicious anemia ... Clinical Manifestations ... antibody that works ... Management #treatment #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... • Bilateral signs ... Check Vitamin B12 ... • Nutritional Deficiency ... diagnosis #management #neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... • Symptoms and signs ... myelopathy - Vit B12 ... MCTD, Sjogren syndrome ... #diagnosis #neurology
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