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diagnosis management algorithm sclerosis spinalcord weakness alkaline alp als amyotrophic arteritis behcet causes disorders fatigue gca giantcell hepatology hyophosphatasia ibd
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... gestation • Vitamin B12 ... #differential # ... diagnosis #signs ... #symptoms #nutrition
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... lesion: Clinical ... and signs below ... myelopathy - Vit B12 ... Sarcoidosis, Behcet disease
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
cord - Spinal Cord ... result in permanent neurologic ... HIV) - Vitamin B12 ... , Copper deficiency ... #lesions #differential
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... • Bilateral signs ... and/or symptoms ... • Nutritional Deficiency ... #differential
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness • Spinal ... Cord: Demyelinating ... : Acid maltase deficiency ... Weakness #Causes #differential ... #diagnosis #neurology
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
fatigue despite clinical ... Receptor (sTfR) to differentiate ... restricted diet/deficiency ... symptoms even if ... fatigue despite disease
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... white matter, spinal ... cord, and basal ... ) Differential Diagnosis ... diagnosis #management #signs
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... Signs and symptoms ... stimulation Clinical ... Progressive MS (Spinal ... cord predominant
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Lesions of the spinal ... cord • Inflammatory ... endocrine: Vitamin B12 ... deficiency • ... Lack of UMN/LMN signs
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Presentation: - Disease ... cord regions of ... fasciculations Common Symptoms ... conditions listed in differential ... Lateral #Sclerosis #neurology
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