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diagnosis hematology management nutrition syndromes algorithm alkaline alp bariatric bypass classification cobalamin cord deficiencies dementia folate folicacid gastric geriatrics hepatology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
evaluation of macrocytic ... the most likely cause ... B12 deficiency ... deficiency. ... #AAFP
Micronutrient Deficiencies After Gastric Bypass Fat-Soluble Vitamins: • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
• Thiamine - Nausea ... oculomotor dysfunction, gait ... anemia • Vitamin ... B12 - Macrocytic ... nutrition #table #differential
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
MCV - >96fL - "Macrocytic ... Megaloblastic: Vitamin ... B12 deficiency, ... morphologic #mcv #differential ... #diagnosis #causes
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... • Common Causes ... intrinsic factor, IF) Clinical ... : • Worsening macrocytic ... parasthesias, gait
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
1) Clinical ... syphilis, Whipple, vitamin ... deficiency, ... ... - Progressive amnesia ... MNCD #Dementia #Differential
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... • Vitamin C deficiency ... • Pernicious anemia ... /B12 deficiency ... ) - Waddling gait
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... common cytopenia: Macrocytic ... • Nutritional: vitamin ... B12 or folic acid ... blood count with differential
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... , and HIV) - Vitamin ... B12, Copper deficiency ... syndromes #lesions #differential ... #diagnosis #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... • Nutritional Deficiency ... : - Vitamin B12 ... diagnosis #management #neurology ... #differential
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