11 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach ... Diagnosis Algorithm ... • B12/Folate ... #Algorithm #Causes ... #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Diagnostic Framework ... Approach - MCV) ... Megaloblastic: Vitamin B12 ... #differential #diagnosis ... #causes #hematology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... #diagnosis #management
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... • Pernicious anemia ... /B12 deficiency ... ) - Waddling gait
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... restricted diet/deficiency ... /other causes • ... IBD #Algorithm #diagnosis ... #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... #oncology #hematology ... #diagnosis #management
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... Incubation period: 3-12 ... severe hemolytic anemia ... #management #Bartonella
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
and Management ... and pernicious anemia ... Clinical Manifestations ... • Wide based gait ... #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Check Vitamin B12 ... • Nutritional Deficiency ... : - Vitamin B12 ... #management #neurology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... systemic complaints- anemia ... identifies 85 to 95% of cases ... #Management