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diagnosis differential management algorithm cord macrocytic oncology spinal syndromes alkaline alp aplastic approach classification cobalamin elevatedmcv evaluation falls fat fatrbc
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Dietary Deficiency ... • Small Bowel Disorder ... and Folate Deficiency ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
• B12/Folate ... Deficiency • Aplastic ... • RBC Membrane Disorder ... Diagnosis #Algorithm #Causes ... #Hematology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... dysfunction, and/or disorders ... intrinsic factor, IF) Clinical ... parasthesias, gait
FAT RBC Mnemonic for Causes of Macrocytic Anemia (MCV > 100) F - Folate (Fetus) and B12 Deficiency
RBC Mnemonic for Causes ... Folate (Fetus) and B12 ... Deficiency - Impairs ... - Bone Marrow Disorders ... Differential #Diagnosis #Hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic ... ) - Waddling gait ... Phosphatase: • Other causes
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Pancytopenia is a hematologic ... well as varying clinical ... that involves disorders ... These causes could
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... #oncology #hematology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... of injury • Gait ... myelopathy - Vit B12 ... #spinal #cord #spinalcord ... #neurology #differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... caused by blood ... Nutritional: vitamin B12 ... or folic acid deficiency ... Syndromes #diagnosis #hematology
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... HIV) - Vitamin B12 ... , Copper deficiency ... unilateral) #SpinalCord ... differential #diagnosis #neurology
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