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diagnosis management differential algorithm spinalcord alkaline alp als amyotrophic aplastic cobalamin disorders emergencies evaluation falls fatigue geriatrics hematology hemeonc hepatology
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
cord - Spinal Cord ... result in permanent neurologic ... Causes of spinal ... HIV) - Vitamin B12 ... , Copper deficiency
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... lesion: Clinical ... of injury • Gait ... Cord Causes: 1 ... myelopathy - Vit B12
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
Inhibited Pathway caused ... cord, which is ... deficiency. ... The classic clinical ... of pernicious anemia
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Hyperreflexia develops later ... Bilateral signs and/or symptoms ... • Infectious causes ... • Nutritional Deficiency
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... , alcohol use, symptoms
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
fatigue despite clinical ... restricted diet/deficiency ... symptoms even if ... wnl B12 Patient ... /other causes •
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... • Improve the symptoms ... #oncology #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• Pernicious anemia ... /B12 deficiency ... mineralization Symptoms ... respiratory failure • Neurologic ... ) - Waddling gait
The Stages of Syphilis Primary Syphilis - The chancre lesion is the hallmark of primary syphilis.
soles in 50% of cases ... exposure to or symptoms ... tabes dorsalis, gait ... similar to those of B12 ... deficiency.
Evaluation of Recurrent Falls Core Concept: Maintaining an upright posture requires the integrated function of multiple systems. Disruption in
embolism - Severe anemia ... presyncope, exertional symptoms ... e.g., diabetic, B12 ... deficiency) ... - Spinal cord disorders
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