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diagnosis management differential hematology spinal spinalcord algorithm alkaline alp aplastic cobalamin disorders hepatology hyophosphatasia latent lesions low mds myelitis myelodysplasia
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... result in permanent neurologic ... HIV) - Vitamin B12 ... , Copper deficiency ... Lower motor neuron symptoms
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... • Improve the symptoms ... #oncology #hematology
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
a syndrome identical ... of the spinal cord ... deficiency. ... The classic clinical ... of pernicious anemia
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... , alcohol use, symptoms
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... of injury • Gait ... Causes: 1. ... myelopathy - Vit B12 ... MCTD, Sjogren syndrome
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... • Pernicious anemia ... /B12 deficiency ... mineralization Symptoms ... ) - Waddling gait
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Nutritional: vitamin B12 ... or folic acid deficiency ... treatments • Copper deficiency ... diagnosis #hematology #oncology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Bilateral signs and/or symptoms ... Check Vitamin B12 ... • Nutritional Deficiency ... diagnosis #management #neurology
The Stages of Syphilis Primary Syphilis - The chancre lesion is the hallmark of primary syphilis.
soles in 50% of cases ... exposure to or symptoms ... tabes dorsalis, gait ... similar to those of B12 ... deficiency.
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
and pernicious anemia ... brain and spinal cord ... Clinical Manifestations ... • Wide based gait ... Management #treatment #neurology
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