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diagnosis differential management aids alkaline alp aplastic cobalamin emergencies evaluation falls geriatrics hematology hemeonc hepatology hiv hyophosphatasia immune infections infectiousdiseases
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
membrane into the CNS ... • Pernicious anemia ... /B12 deficiency ... mineralization Symptoms ... ) - Waddling gait
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... , alcohol use, symptoms
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
reactivation of latent ... • IRIS might ... should be based on clinical ... , limb ataxia, gait ... patients with IRIS
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... • Improve the symptoms ... may result from low ... #oncology #hematology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
acid, high LDH, low ... high d-dimer, low ... Treat underlying cause ... : CNS changes, headache ... fever, weight gain
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
• AIDS with low ... noncompliance • Clinical ... initiation Clinical ... pleural effusions, CNS ... blindness, or gait
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Transverse Myelitis - Clinical ... Hyperreflexia develops later ... • Infectious causes ... • Nutritional Deficiency
Evaluation of Recurrent Falls Core Concept: Maintaining an upright posture requires the integrated function of multiple systems. Disruption in
embolism - Severe anemia ... presyncope, exertional symptoms ... e.g., diabetic, B12 ... deficiency) ... Evaluation #Geriatrics #Neurology
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