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diagnosis management differential pathophysiology algorithm alkaline alp anorexianervosa aplastic arteritis cobalamin cord disorders evaluation falls gca geriatrics giantcell hepatology hyophosphatasia
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... , alcohol use, symptoms
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• Pernicious anemia ... /B12 deficiency ... mineralization Symptoms ... ) - Waddling gait ... Phosphatase: • Other causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... • Improve the symptoms ... #oncology #hematology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... and signs below ... of injury • Gait ... Non-compressive Spinal Cord Causes ... myelopathy - Vit B12
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
Pathogenesis and Clinical ... Incr PVR if a complication ... SUI or UUI not caused ... Pathophysiology #Signs ... #Symptoms #Urology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... and ophthalmic complications ... Diagnosis = clinical ... systemic sx + signs ... systemic complaints- anemia
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... • Bilateral signs ... and/or symptoms ... • Infectious causes ... • Nutritional Deficiency
Evaluation of Recurrent Falls Core Concept: Maintaining an upright posture requires the integrated function of multiple systems. Disruption in
embolism - Severe anemia ... presyncope, exertional symptoms ... e.g., diabetic, B12 ... deficiency) ... positive Romberg sign
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
/ Hypovolemia NEUROLOGIC ... and memory loss HEMATOLOGIC ... lymphocytosis, mild anemia ... from nutrient deficiency ... #symptoms #psychiatry
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