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diagnosis management differential algorithm spinalcord alkaline alp als amyotrophic aplastic cobalamin disorders evaluation falls geriatrics hematology hepatology hyophosphatasia lateral lesions
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
Fatigue and IBD ... despite clinical ... restricted diet/deficiency ... symptoms even if ... /other causes •
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
cord - Spinal Cord ... result in permanent neurologic ... Causes of spinal ... HIV) - Vitamin B12 ... , Copper deficiency
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... lesion: Clinical ... of injury • Gait ... Cord Causes: 1 ... myelopathy - Vit B12
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... slowing, neuropathy, fatigue ... parasthesias, gait
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
Inhibited Pathway caused ... cord, which is ... deficiency. ... The classic clinical ... of pernicious anemia
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Bilateral signs and/or symptoms ... Check Vitamin B12 ... • Nutritional Deficiency ... diagnosis #management #neurology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... : • Fever • Fatigue ... and petechiae Causes ... , GATA2 deficiency ... • Improve the symptoms
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... • Pernicious anemia ... /B12 deficiency ... mineralization Symptoms ... ) - Waddling gait
Evaluation of Recurrent Falls Core Concept: Maintaining an upright posture requires the integrated function of multiple systems. Disruption in
embolism - Severe anemia ... presyncope, exertional symptoms ... e.g., diabetic, B12 ... deficiency) ... - Spinal cord disorders
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
cord regions of ... - Causes progressive ... fasciculations Common Symptoms ... : - Fatigue and ... Lateral #Sclerosis #neurology
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