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diagnosis management differential algorithm hematology oncology spinalcord syndrome syndromes acute alkaline alp als amyotrophic aplastic arteritis cobalamin disorders evaluation falls
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
cord - Spinal Cord ... result in permanent neurologic ... Causes of spinal ... HIV) - Vitamin B12 ... , Copper deficiency
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... lesion: Clinical ... of injury • Gait ... Cord Causes: 1 ... myelopathy - Vit B12
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... slowing, neuropathy, fatigue ... parasthesias, gait
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
despite clinical ... Crohn's > UC Anemia ... restricted diet/deficiency ... symptoms even if ... /other causes •
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
Inhibited Pathway caused ... cord, which is ... deficiency. ... The classic clinical ... of pernicious anemia
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• Pernicious anemia ... /B12 deficiency ... mineralization Symptoms ... respiratory failure • Neurologic ... ) - Waddling gait
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Bilateral signs and/or symptoms ... Check Vitamin B12 ... • Nutritional Deficiency ... diagnosis #management #neurology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... : • Fever • Fatigue ... and petechiae Causes ... • Improve the symptoms ... may result from low
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... : • Fatigue • ... Nutritional: vitamin B12 ... or folic acid deficiency ... treatments • Copper deficiency
Evaluation of Recurrent Falls Core Concept: Maintaining an upright posture requires the integrated function of multiple systems. Disruption in
embolism - Severe anemia ... presyncope, exertional symptoms ... e.g., diabetic, B12 ... deficiency) ... - Spinal cord disorders
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