14 results
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
cord - Spinal Cord ... result in permanent neurologic ... Causes of spinal ... HIV) - Vitamin B12 ... , Copper deficiency
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
despite clinical ... restricted diet/deficiency ... symptoms even if ... /other causes • ... Algorithm #diagnosis #management
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... lesion: Clinical ... of injury • Gait ... Cord Causes: 1 ... myelopathy - Vit B12
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
Inhibited Pathway caused ... cord, which is ... deficiency. ... The classic clinical ... of pernicious anemia
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... intrinsic factor, IF) Clinical ... slowing, neuropathy, fatigue ... parasthesias, gait ... #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Bilateral signs and/or symptoms ... • Infectious causes ... • Nutritional Deficiency ... #neurology #differential
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... : • Fever • Fatigue ... and petechiae Causes ... • Improve the symptoms ... hematology #diagnosis #management
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... • Pernicious anemia ... /B12 deficiency ... mineralization Symptoms ... ) - Waddling gait
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
: • CENTRAL: Fatigue ... stimulation Clinical ... Progressive MS (Spinal ... cord predominant ... sclerosis #diagnosis #management
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
cord regions of ... - Causes progressive ... fasciculations Common Symptoms ... : - Fatigue and ... #diagnosis #management