12 results
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework
LOW RETIC INDEX - ↓ PRODUCTION
 • Vitamin
Causes of Anemia ... in Cirrhosis - ... PRODUCTION • Vitamin B12 ... #Cirrhosis #Differential ... #Diagnosis #Hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• Pernicious anemia ... /B12 deficiency ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... ) - Waddling gait
FAT RBC Mnemonic for Causes of Macrocytic Anemia
(MCV > 100)

F - Folate (Fetus) and B12 Deficiency
RBC Mnemonic for Causes ... Folate (Fetus) and B12 ... Deficiency - Impairs ... leukemia) C - Cirrhosis ... Differential #Diagnosis #Hematology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... #Cobalamin #Deficiency
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
Inhibited Pathway caused ... deficiency. ... The classic clinical ... of pernicious anemia ... #Pathophysiology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... #oncology #hematology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
and pernicious anemia ... Person Syndrome Pathophysiology ... Clinical Manifestations ... • Wide based gait ... Management #treatment #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... • Infectious causes ... • Nutritional Deficiency ... diagnosis #management #neurology
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
embolism - Severe anemia ... e.g., diabetic, B12 ... deficiency) ... range of motion, gait ... Evaluation #Geriatrics #Neurology
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
Crisis (SRC) Clinical ... microangiopathic hemolytic anemia ... (MAHA) Pathophysiology ... • Refractory cases ... #nephrology #diagnosis