24 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• Pernicious anemia ... /B12 deficiency ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... ) - Waddling gait
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... #diagnosis #management
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Pathogenesis and clinical ... Chondrodysplasia Neurologic ... #pathophysiology ... #causes #symptoms ... #signs #diagnosis
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
Inhibited Pathway caused ... deficiency. ... The classic clinical ... of pernicious anemia ... #Pathophysiology
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... Crohn's > UC Anemia ... restricted diet/deficiency ... /other causes • ... Algorithm #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... hematology #diagnosis #management
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
Pathogenesis and Clinical ... Deficiency in galactosylation ... Intussusception - Renal ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
of lactate as a clinical ... malignancy, or thiamine deficiency ... 30mmHg) - Severe anemia ... effect - Thiamine deficiency ... - Renal failure
Varicocele: Pathogenesis and clinical findings
Primary:
 - Anatomically: the left spermatic vein drains into the left renal
Pathogenesis and clinical ... retroperitoneal masses ... #Varicocele #Pathophysiology ... #Signs #Symptoms ... #Urology #Diagnosis
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Scurvy (Vitamin C Deficiency ... Diagnosis and Management ... poor nutrition Clinical ... Loss of teeth Anemia ... , or any other cause