22 results
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
dysfunction (e.g. gait ... development of Korsakoff ... syndrome (chronic ... B1 deficiency) ... #neurology #nutrition
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
Encephalopathy vs Korsakoff ... Syndrome - Thiamine ... ataxia (broad-based gait ... and retrograde amnesia ... #comparison #neurology
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Beri-beri, Wernicke-Korsakoff ... syndrome • Riboflavin ... gestation • Vitamin B12 ... signs #symptoms #nutrition
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
Korsakoff Syndrome ... Clinical Findings ... • Anterograde amnesia ... presentation of Thiamine deficiency ... #Syndrome #neurology
Micronutrient Deficiencies After Gastric Bypass
Fat-Soluble Vitamins:
 • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
oculomotor dysfunction, gait ... ataxia), Korsakoff ... syndrome (amnesia ... • Vitamin B12 ... Bypass #vitamin #nutrition
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency ... Framework and Clinical ... Manifestations Causes ... consistent with WKS • Korsakoff ... #beriberi #nutrition
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... intrinsic factor, IF) Clinical ... parasthesias, gait ... #diagnosis #management ... #nutrition
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
• Metabolic / Nutritional ... : DiabetesB12 deficiency ... Paraprotein-associated (POEMS syndrome ... differential #diagnosis #causes ... #neurology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... hematology #diagnosis #management
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
Inhibited Pathway caused ... a syndrome identical ... deficiency. ... The classic clinical ... of pernicious anemia