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diagnosis hematology management alkaline alp aplastic cord differential disorders hepatology hyophosphatasia low mds myelodysplasia myelodysplastic person phosphatase spinal spinalcord sps
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Nutritional: vitamin B12 ... or folic acid deficiency ... Workup: • Complete ... diagnosis #hematology #oncology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... • Pernicious anemia ... /B12 deficiency ... ) - Waddling gait ... Phosphatase: • Other causes
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
and pernicious anemia ... Clinical Manifestations ... • Wide based gait ... antibody that works ... Management #treatment #neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... of injury • Gait ... myelopathy - Vit B12 ... MCTD, Sjogren syndrome ... differential #algorithm
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