15 results
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... gestation • Vitamin B12 ... differential #diagnosis #signs ... #symptoms #nutrition
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... intrinsic factor, IF) Clinical ... to IBD, celiac disease ... #diagnosis #management ... #nutrition
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... restricted diet/deficiency ... symptoms even if ... fatigue despite disease ... /other causes
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... • Improve the symptoms ... hematology #diagnosis #management
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Scurvy (Vitamin C Deficiency ... Diagnosis and Management ... Clinical Presentation ... Psychiatric symptoms ... , or any other cause
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Malnutrition • Wilson's disease ... • Pernicious anemia ... /B12 deficiency ... mineralization Symptoms ... Phosphatase: • Other causes
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... and signs below ... hematogenous spread - Fungal ... myelopathy - Vit B12 ... Sarcoidosis, Behcet disease
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... • Bilateral signs ... and/or symptoms ... Deficiency: - ... #neurology #differential
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Myeloproliferative Disease ... Platelet Disorders • Nutritional ... : vitamin B12 or ... folic acid deficiency
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Diagnosis and Management ... caused by the protozoan ... Romana's sign ... /symptoms, positive ... serology, smear