83 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... • Dietary Deficiency ... Myelodysplastic Syndromes ... and Folate Deficiency ... • Liver Disease
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Diagnostic Framework ... chronic kidney disease ... Megaloblastic: Vitamin B12 ... Myelodysplastic syndrome ... #differential #diagnosis
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... Wernicke-Korsakoff syndrome ... gestation • Vitamin B12 ... #differential #diagnosis
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
- Differential Diagnosis ... : • GATA2 deficiency ... • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... consumption • Vitamin B12
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
Clinical Findings ... initial phase of the disease ... • Anterograde amnesia ... presentation of Thiamine deficiency ... #neurology #diagnosis
Criss-Cross Gait on Physical Exam 

Seen in Glucose Transporter type 1 Deficiency Syndrome

#CrissCross #Criss #Cross #Gait
Transporter type 1 Deficiency ... Syndrome #CrissCross ... #PhysicalExam #clinical ... #video #neurology ... #GLUT1 #deficiency
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
- Thiamine Deficiency ... and retrograde amnesia ... #vitaminB1 #B1 # ... #diagnosis #comparison ... #neurology
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Management Diagnosis ... development of Korsakoff syndrome ... (chronic B1 deficiency ... #Diagnosis #Management ... #neurology #nutrition
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
with anemia, diagnose ... iron deficiency ... Test for celiac disease ... change medical management ... Evaluation #workup #diagnosis
Causes of Low Vitamin B12 Levels
Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people
Autoimmune
of Low Vitamin B12 ... Levels Low vitamin B12 ... and Sjögren's syndrome ... , coeliac disease ... #differential #diagnosis