42 results
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... - Coagulation disorder ... Wernicke-Korsakoff syndrome ... diagnosis #signs #symptoms
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
• Dietary Deficiency ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... and Folate Deficiency ... • Liver Disease
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... dysfunction, and/or disorders ... intrinsic factor, IF) Clinical ... to IBD, celiac disease ... #diagnosis #management
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Diagnosis and Management ... treatment can improve symptoms ... development of Korsakoff syndrome ... (chronic B1 deficiency ... #neurology #nutrition
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
Clinical Findings ... initial phase of the disease ... • Anterograde amnesia ... presentation of Thiamine deficiency ... #neurology #diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... , GATA2 deficiency ... , CTLA4 deficiency ... • Improve the symptoms ... hematology #diagnosis #management
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... restricted diet/deficiency ... symptoms even if ... fatigue despite disease ... Algorithm #diagnosis #management
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... of anemia include ... • hemolytic anemia ... #hemolytic #anemia
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
, deficiency of ... paralyses CNS Disorders ... • Tumor lysis syndrome ... polyangiitis • Behçet's syndrome ... associated with any symptoms
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... (AQP4-lgG disease ... Comorbid autoimmune disorders ... Manifestations #diagnosis #neurology ... #symptoms #signs