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diagnosis algorithm differential management elevatedmcv oncology aafp alkaline alp aplastic cobalamin fat fatigue fatrbc folate folicacid hepatology homocysteine hyophosphatasia ibd
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Drugs Oval Macrocytes ... • Dietary Deficiency ... #Anemia #Macrocytosis ... #Hematology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
evaluation of macrocytic ... the most likely cause ... recovery also causes ... deficiency. ... #Macrocytic #Anemia
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic ... Anemia • 812 ... , Folate Deficiency ... diagnosis #algorithm #hematology ... #workup
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
" • Iron deficiency ... MCV - >96fL - "Macrocytic ... Megaloblastic: Vitamin B12 ... differential #diagnosis #causes ... #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... RBC>13 • Iron Deficiency ... #Microcytic #Anemia ... #Macrocytosis # ... #Hematology
FAT RBC Mnemonic for Causes of Macrocytic Anemia (MCV > 100) F - Folate (Fetus) and B12 Deficiency
of Macrocytic Anemia ... Folate (Fetus) and B12 ... Deficiency - Impairs ... #Macrocytic #Anemia ... Differential #Diagnosis #Hematology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... intrinsic factor, IF) Clinical ... : • Worsening macrocytic ... hypersegmented neutrophils, macrocytosis
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
fatigue despite clinical ... Crohn's > UC Anemia ... If persistent macrocytosis ... restricted diet/deficiency ... /other causes •
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... MCV 80-100 fl) & macrocytic ... Pancytopenia is a hematologic ... well as varying clinical ... These causes could
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... #oncology #hematology
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