21 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
B12/Folate ... Deficiency • Aplastic ... • RBC Membrane Disorder ... #Classification ... Diagnosis #Algorithm #Causes
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
serum level for all ... the most likely cause ... recovery also causes ... of the initial work-up ... deficiency.
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... not required in all ... #Workup #hematology
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
neurocognitive disorders ... 1) Clinical ... Whipple, vitamin deficiency ... - Progressive amnesia ... Differential #Subtypes #Classification
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... dysfunction, and/or disorders ... intrinsic factor, IF) Clinical ... #Cobalamin #Deficiency
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... Crohn's > UC Anemia ... & Fe Sucrose > alt ... restricted diet/deficiency ... /other causes
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
ILD, OSA, pHTN, Anemia ... Polyneuropathy, ALS ... ), NMJ disorder ... Differential #Diagnosis #causes ... #neurology
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
a decrease in all ... hemoglobin of less than 12 ... well as varying clinical ... that involves disorders ... These causes could
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Nutritional: vitamin B12 ... or folic acid deficiency ... Workup: • Complete