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differential management hematology b1 causes encephalopathy korsakoff oncology syndromes thiamine acidosis alkaline alp aplastic cobalamin comparison cord dementia elevation erythematosus
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... Wernicke-Korsakoff syndrome ... #differential #diagnosis ... signs #symptoms #nutrition
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management Diagnosis - Caine Criteria (2 of
- Diagnosis and ... Management Diagnosis ... development of Korsakoff syndrome ... (chronic B1 deficiency ... #neurology #nutrition
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
- Differential Diagnosis ... • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis Nutritional ... consumption • Vitamin B12
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency Wernicke's encephalopathy is a neurological condition due to longstanding
- Thiamine Deficiency ... and retrograde amnesia ... #vitaminB1 #B1 # ... #diagnosis #comparison ... #neurology
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
1) Clinical diagnosis ... Whipple, vitamin deficiency ... Aphaso-apraxo-agnosia syndrome ... Differential #Subtypes #Classification ... #Workup #Diagnosis
Etiologies of Peripheral Neuropathy • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism • Medication-induced: ART, Antibiotics,
• Metabolic / Nutritional ... : DiabetesB12 deficiency ... Paraprotein-associated (POEMS syndrome ... #differential #diagnosis ... #causes #neurology
Korsakoff Syndrome Clinical Findings: • Confabulation: Usually initial phase of the disease • Anterograde amnesia: Memory impairment
Korsakoff Syndrome ... Clinical Findings ... • Anterograde amnesia ... presentation of Thiamine deficiency ... #neurology #diagnosis
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... intrinsic factor, IF) Clinical ... #Cobalamin #Deficiency ... #diagnosis #management ... #nutrition
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... , GATA2 deficiency ... , CTLA4 deficiency ... - Parvovirus B19 ... oncology #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Platelet Disorders • Nutritional ... : vitamin B12 or ... Workup: • Complete ... #diagnosis #hematology
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