11 results
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
serum level for all ... of the initial work-up ... deficiency is present ... deficiency. ... #VitaminB12 #Folate
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... gestation • Vitamin B12 ... #differential # ... signs #symptoms #nutrition
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Tetanus, Transverse Myelitis ... Motor Nerves: ALS ... : Acid maltase deficiency ... Weakness #Causes #differential ... #diagnosis #neurology
Etiologies of Vitamin B12 Deficiency
 • Inadequate intake - Rare but seen in very strict vegans
deficiency. ... autoantibodies (pernicious anemia ... #VitaminB12 #deficiency ... #differential # ... diagnosis #hematology #nutrition
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
ILD, OSA, pHTN, Anemia ... Rhabdomyolysis, Critical ... Polyneuropathy, ALS ... Inflammatory/Rheum: Myositis ... Diagnosis #causes #neurology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... is critical for ... • Pernicious anemia ... /B12 deficiency ... respiratory failure • Neurologic
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... Crohn's > UC Anemia ... & Fe Sucrose > alt ... Receptor (sTfR) to differentiate ... restricted diet/deficiency
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... endocrine: Vitamin B12 ... deficiency • ... dystrophies Work ... #Diagnosis #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
- Clinical Presentation ... antibodies • Nutritional ... Deficiency: - ... diagnosis #management #neurology ... #differential
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Platelet Disorders • Nutritional ... : vitamin B12 or ... Workup: • Complete ... blood count with differential