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diagnosis differential hematology management causes algorithm vitaminb12 b1 classification encephalopathy korsakoff macrocytosis oncology syndromes thiamine vitamin aafp acidosis alkaline alp
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic ... Anemia • 812 ... , Folate Deficiency ... #Anemia #differential ... algorithm #hematology #workup
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
" • Iron deficiency ... MCV - >96fL - "Macrocytic ... Megaloblastic: Vitamin B12 ... deficiency • ... Myelodysplastic syndrome
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
• Drugs Oval Macrocytes ... • Dietary Deficiency ... Myelodysplastic Syndromes ... and Folate Deficiency ... Liver Disease #Macrocytic
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
evaluation of macrocytic ... of the initial work-up ... deficiency is present ... deficiency. ... #Macrocytosis #Macrocytic
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... Wernicke-Korsakoff syndrome ... gestation • Vitamin B12 ... signs #symptoms #nutrition
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management Diagnosis - Caine Criteria (2 of
upper limb) • Nutritional ... development of Korsakoff syndrome ... (chronic B1 deficiency ... Diagnosis #Management #neurology ... #nutrition
Micronutrient Deficiencies After Gastric Bypass Fat-Soluble Vitamins: • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
ataxia), Korsakoff syndrome ... cardiomyopathy) • Folate - Macrocytic ... anemia • Vitamin ... B12 - Macrocytic ... Bypass #vitamin #nutrition
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diseases: • GATA2 deficiency ... • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis Nutritional ... consumption • Vitamin B12
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... intrinsic factor, IF) Clinical ... : • Worsening macrocytic ... #Cobalamin #Deficiency ... diagnosis #management #nutrition
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency Wernicke's encephalopathy is a neurological condition due to longstanding
- Thiamine Deficiency ... thiamine (vitamin B1 ... and retrograde amnesia ... #vitaminB1 #B1 # ... diagnosis #comparison #neurology
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