18 results
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
- "Microcytic" ... - "Macrocytic" ... Megaloblastic: Vitamin B12 ... Myelodysplastic syndrome ... diagnosis #causes #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Microcytic ( ... inflammation) • Iron deficiency ... Infections Macrocytic ... , B12 deficiency ... Differential #Diagnosis #hematology
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypoproliferative Macrocytic ... Anemia812 ... , Folate Deficiency ... diagnosis #algorithm #hematology ... #workup
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Corpuscular Volume (MCV ... • Drugs Oval Macrocytes ... • Dietary Deficiency ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
(cell) volume (MCV ... (EPO), iron or B12 ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic ... #Macrocytic
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... Wernicke-Korsakoff syndrome ... #Vitamins #Deficiency ... signs #symptoms #nutrition
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
• Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis Nutritional ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... anemia (MCV<80 ... & macrocytic anemia ... Pancytopenia is a hematologic ... well as varying clinical
FAT RBC Mnemonic for Causes of Macrocytic Anemia
(MCV > 100)

F - Folate (Fetus) and B12 Deficiency
for Causes of Macrocytic ... Anemia (MCV > ... Folate (Fetus) and B12 ... Deficiency - Impairs ... #Diagnosis #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... , GATA2 deficiency ... , CTLA4 deficiency ... - Parvovirus B19 ... #oncology #hematology