10 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Neutrophils - Low RBC ... Myelodysplastic Syndromes ... Cells, Normal WBCs ... #Differential #Diagnosis
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Even with normal WBC ... relative to both WBC ... 21% had normal WBC ... #neutrophil #WBC ... #CBC #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... Anemia #oncology #hematology ... #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Clinical ... Can begin in arms ... Guillain-Barre Diagnosis ... - NORMAL CSF WBC ... #diagnosis #management
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
Hippocrates in 5 BC ... immunosuppressive meds ... rash #cellulitis #dermatology ... #legs #clinical ... #photo
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
capillary leak syndrome ... +Organomegaly+↑RBC ... Thrombosis in vascular beds-renal ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... Lymphocytosis on CBC ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... Blood smear - RBC ... hemolytic #anemia #hematology ... #diagnosis
Symmetrical Drug-Related Intertriginous and Flexural Exanthema (SDRIFE)

49M +burning rash groins/buttocks (pic in next thread) x 1d.
WBC: 9. ... known as baboon syndrome ... Exanthema #rash #clinical ... #photo #dermatology
Hepatopulmonary Syndrome - Illness Script
HPS is a pulmonary disorder of chronic liver disease characterized by a
overperfusion + decreased RBC ... of orthodeoxia CLINICAL ... digital clubbing DIAGNOSIS ... mortality rate of ~12% ... #cirrhosis #diagnosis