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diagnosis management cord spinalcord weakness algorithm behcet causes disease disorders encephalopathy gitelman gravis hypokalemia lesions myasthenia myelitis neuromuscular pathophysiology posterior
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness • Spinal ... heavy metals), Critical ... Shellfish poisoning, Meds ... Weakness #Causes #differential ... #diagnosis #neurology
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
Syndromes Spinal ... result in permanent neurologic ... HIV) - Vitamin B12 ... #lesions #differential ... #diagnosis #neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
- Differential ... neurological lesion: Clinical ... myelopathy - Vit B12 ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Lesions of the spinal ... endocrine: Vitamin B12 ... #Weakness #Differential ... #Diagnosis #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
brain PRES Clinical ... may precede the neurologic ... Reversible course Differential ... Seizures: Treat with AEDs ... diagnosis #management #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Check Vitamin B12 ... Deficiency: - Vitamin B12 ... diagnosis #management #neurology ... #differential
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... white matter, spinal ... (Clinical Dx). ... oral ulcers in 12 ... Behcet disease) Differential
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Clinical Picture ... life-threatening Differential ... Clinical DX: - ... immunosuppressants - Meds ... diagnosis #management #neurology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... present in the apical ... tubule (DCT) Clinical ... ratio 0.5%) Differential ... #diagnosis #nephrology
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