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diagnosis cord spinalcord weakness algorithm behcet causes disease disorders encephalopathy gitelman gravis hypokalemia lesions ms multiple myasthenia neuromuscular pathophysiology posterior
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness • Spinal ... Tetanus, Transverse Myelitis ... heavy metals), Critical ... Weakness #Causes #differential ... #diagnosis #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
- Clinical Presentation ... Check Vitamin B12 ... Deficiency: - Vitamin B12 ... #diagnosis #management ... #neurology #differential
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Lesions of the spinal ... endocrine: Vitamin B12 ... #Weakness #Differential ... #Diagnosis #neurology
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
Syndromes Spinal ... result in permanent neurologic ... HIV) - Vitamin B12 ... #lesions #differential ... #diagnosis #neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... - Transverse myelitis ... myelopathy - Vit B12 ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Reversible course Differential ... Seizures: Treat with AEDs ... #diagnosis #management ... #neurology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... white matter, spinal ... (Clinical Dx). ... Behcet disease) Differential ... #diagnosis #management
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neuritis • Partial myelitis ... • Or brainstem syndromes ... Progressive MS (Spinal ... sclerosis #diagnosis #management ... #neurology #treatment
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Clinical Picture ... life-threatening Differential ... immunosuppressants - Meds ... Gravis #diagnosis #management ... #neurology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
present in the apical ... tubule (DCT) Clinical ... ratio 0.5%) Differential ... #diagnosis #nephrology ... #management #pathophysiology
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