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differential management clinical myasthenia rheumatology algorithm altitude amyotrophic autoimmune bilateral blines cns cord disorders edema encephalitis endocrinology eyelid hape high
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal ... Motor Nerves: ALS ... Syndrome, Myasthenia Gravis ... #diagnosis #neurology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Generalized fatigue - ALS ... myasthenia Diagnosis ... test - Cogan sign ... - Peek sign ... #neurology
Ocular Myasthenia Gravis on Physical Exam A 41yo female was referred by her neurologist for double vision.
non-localized EOM weakness ... cogan sign and ... dismay the blood work ... PhysicalExam #clinical #video ... ophthalmology #neurology
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 Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
- Causes progressive ... of UMN and LMN signs ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
endocrine: Vitamin B12 ... Postsynaptic: Myasthenia Gravis ... Lack of UMN/LMN signs ... dystrophies Work ... #neurology
Bilateral B-Lines in case of Pneumonia on Lung POCUS Young healthy pt with fever/dyspnea. POCUS lung exam
Bilateral B-Lines in case ... interstitial lung disease ... Also has partially ... seen shred sign ... NOT definitively diagnose
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 Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension - Workup ... and Differential Diagnosis ... hypertension and signs ... renal bruit or signs ... Renal parenchymal disease
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
irregularities • Weakness ... diffuse goiter (Graves ... ' disease is suspected ... hyperthyroidism #causes ... endocrinology #signs
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
• Symptoms and signs ... Non-compressive Spinal Cord Causes ... myelopathy - Vit B12 ... Sarcoidosis, Behcet disease ... #neurology #differential
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... Check Vitamin B12 ... • Infectious causes ... Deficiency: - Vitamin B12 ... #management #neurology
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