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management differential neurology pediatrics rheumatology symptoms algorithm antinxp2 behcet brain brudzinskis causes cop crypto cryptococcal cryptogenic dermatology dermatomyositis endocrinology gravis
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski) Brudzinski's sign is characterized
Brudzinski’s Sign ... Brudzinski's sign ... despite severe disease ... #Meningitis #Clinical ... #Pediatrics #Peds
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 Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Neck: “dropping ... myasthenia Diagnosis ... test - Cogan sign ... - Peek sign ... Myasthenia #Gravis #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... lesions, aseptic meningitis ... oral ulcers in 12 ... Arthritis, AS Treatment ... #management #signs
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
Hyperthyroidism Overview Clinical ... Hyperdefecation • Anterior neck ... goiter (Graves' disease ... TRAb) if Graves' disease ... endocrinology #signs
Evaluation of suspected incomplete Kawasaki Disease 1. AHA consensus recommendations 2. Infants ≤6 months old on day ≥7
incomplete Kawasaki Disease ... if they have no clinical ... echo is positive, treatment ... and lab signs ( ... #Diagnosis #Peds
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
weakness in the neck ... chest (in a V-sign ... shoulders (in a shawl sign ... auricular papules Clinical ... had more severe disease
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... • Bilateral signs ... Check Vitamin B12 ... Deficiency: - Vitamin B12 ... Transverse Myelitis Treatment
Cryptogenic Organizing Pneumonia - Illness Script PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Males=Females SIGNS ... : Clinical diagnosis ... identified (autoimmune, meds ... , neoplastic) TREATMENT ... steroids for severe disease
Cryptococcal meningitis on T2 MRI 30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Headache x1 mo, +neck ... organism (soap bubble sign ... Standard treatment ... University Infectious Diseases ... T2 #MRI #Brain #clinical
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