9 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... (CVID, WAS), (neurologic ... #Causes #Workup ... #hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... splenomegaly, abnormal neurology ... Rheumatology ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... , OJ, PL-7, PL-12 ... body-like: - Neurologic ... #differential #diagnosis ... #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... erythematosus (SLE) - Antinuclear ... (to support a diagnosis ... #diagnosis #testing ... #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... oral ulcers in 12 ... ) Differential Diagnosis ... #management #signs ... #symptoms #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
ab • RF • Antinuclear ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Cryoglobulinemia (4%-12% ... Sjogrens #Syndrome #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... noninflammatory Signs ... weeks) Can Be Caused ... • Parvovirus B19 ... #MSK #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... purpura: Strong sign ... affects the skin, neurologic ... tract, and often causes ... #Rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease ... Nutritional: vitamin B12 ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology