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diagnosis neurology signs management pediatrics spinalcord genetics msk spinal syndrome syndromes 21hydroxylasedeficiency 21ohd acute algorithm als alzheimersdisease amyotrophic behcet brudzinskis
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski) Brudzinski's sign is characterized
causes spinal cord ... While the pathophysiology ... an involuntary reflex ... #Meningitis #Clinical ... #Pediatrics #Peds
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 Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... Pathogenesis and clinical ... bladder and rectal reflex ... Syndromes #diagnosis #pathophysiology ... #signs #symptoms
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
- Differential ... neurological lesion: Clinical ... and signs below ... myelopathy - Vit B12 ... dysfunction • Abnormal reflexes
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Pathogenesis and Clinical ... chromosome 21) Signs ... seizure, primitive reflexes ... AlzheimersDisease #Dementia #pathophysiology ... #symptoms
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
HIV) - Vitamin B12 ... Lower motor neuron symptoms ... Upper motor neuron symptoms ... in deep tendon reflexes ... syndromes #lesions #differential
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... Prader-Willi Syndrome Signs ... /Symptoms/Complications ... , sleep apnea, cor ... #peds #pediatrics
Meralgia paresthetica: Pathogenesis and Clinical Findings Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica •
Pathogenesis and Clinical ... gait, strength, reflexes ... MeralgiaParesthetica #MSK #pathophysiology ... #differential # ... diagnosis #signs
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... Spasticity - Reflexes ... • Bilateral signs ... and/or symptoms
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... Signs/Symptoms/Complications ... Late (shock): cold ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... multiple spinal cord ... Increased Jaw Jerk reflex ... fasciculations Common Symptoms ... conditions listed in differential
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