18 results
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Brudzinski’s Sign ... flexion causes spinal ... While the pathophysiology ... an involuntary reflex ... PhysicalExam #Pediatrics #Peds
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
gait, strength, reflexes ... superior iliac spine ... MeralgiaParesthetica #MSK #pathophysiology ... #differential # ... diagnosis #signs
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
- Coagulation disorder ... gestation • Vitamin B12 ... Vitamins #Deficiency #differential ... #diagnosis #signs ... #symptoms #nutrition
Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
Post-Traumatic Stress Disorder ... Exaggerated startle reflex ... BehavioralDisorder #Pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... - Differential ... and signs below ... myelopathy - Vit B12 ... dysfunction • Abnormal reflexes
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
etc) in lumbar spine ... Signs / Symptoms ... of normal leg reflexes ... Syndrome #MSK #pathophysiology ... #signs
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Spasticity - Reflexes ... • Bilateral signs ... and/or symptoms ... management #neurology #differential
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... Syndrome -> Anterior spinal ... bladder and rectal reflex ... Syndromes #diagnosis #pathophysiology ... #signs #symptoms
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Non-neuromuscular disorder ... Lesions of the spinal ... endocrine: Vitamin B12 ... Lack of UMN/LMN signs