42 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Drugs, Unknown cause ... Treatment: • ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... signs and symptoms ... • Bicytopenia Treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
) Treatment Primary ... or autoimmune disease ... , treatment of underlying ... for refractory disease ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... fever syndromes Clinical ... Fever is the main clinical ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management Summary ... present, symptoms, signs ... von Willebrand disease ... Diagnosis #Management #Summary ... #treatment #hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
diagnosis and treatment ... of liver disease ... including liver and hematologic ... diagnosis #management #hepatology ... #gastroenterology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... significant portal HTN Signs ... • Infiltrative diseases ... Veno-occlusive disease ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... months without treatment ... underlying liver disease ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
and Management Summary ... for diagnosis Treatment ... Rifaximin- up to 3 courses ... and Hepatology ... #treatment
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Cirrhosis (PBC) - Summary ... intralobular bile ducts causes ... failure PBC Signs ... but elevated as disease ... diagnosis #workup #hepatology