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diagnosis management hemophagocytic lymphohistiocytosis rheumatology lymphoma syndrome activation chronic classification cll comparison cutaneous dermatology differential hemeonc larva leukemia lymphocytic macrophage
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
e.g., HIV), EBV infection ... • Clinical features ... the spleen or liver ... • Other hematologic ... NonHodgkins #comparison #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Lymphoma - Clinical ... number of sites of disease ... Lymphoma Treatment ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Hemopathies+++: Hodgkin ... • Autoimmune diseases ... Unknown cause Treatment
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... lymph node, or liver ... : • Infection ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Fever is the main clinical ... SLE], AOSD) • Infection ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... weeks without infection ... cells can indicate disease ... microglobulin Treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... ▪ Autoimmune diseases ... Clinical Presentation ... - Elevated liver ... Diagnosis #Management #Hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... vasculitis: 10%-16% Liver ... Nephrogenic DI Hematologic ... Malignancy Risk: • Non-Hodgkins ... Adenocarcinoma Treatment
Cutaneous larva migrans skin Rash 25 F recent Caribbean vacation, walked barefoot on sand and now with
Adult hookworms live ... No treatment is ... one-time dose of 12 ... Diseases Fellowship ... #clinical #photo
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