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diagnosis management dermatology rheumatology syndrome photo cutaneous leukemia rash chronic classification differential hemeonc lymphocytic myelodysplastic acute anemia aplastic behcet blood
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... lymphocytic lymphoma (SLL ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... non-Hodgkin lymphoma SLL ... weeks without infection ... Hepatomegaly • Skin ... #hematology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... Infectious manifestations ... dermatomyositis, SLE ... #oncology #clinical ... #skin
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... : SLE+++, Adult-onset ... Still disease, ... #summary #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... syndrome • Giant cell ... arteritis Infections ... • Fungal infections ... rash #diagnosis #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
) - Summary Overview ... immunophenotype Clinical ... Complications: 1) Infection ... chemotherapy for low-risk disease ... #hematology #hemeonc
Hematuria in Post-Renal Transplant Patient Prevalence up to 12% in the postrenal transplant patient • Bacterial: Escherichia
Simple Virus • Fungal ... : Secondary to infections ... , Busulfan • Disease ... Goodpasture's syndrome, SLE ... urine #management #treatment
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
Vibrio Vulnificus skin ... causes illness in summer ... All oysters at Chesapeake ... chronic liver disease ... #legs #clinical
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... - Purpura - Skin ... Syndrome: • Clinical ... • Autoimmune diseases ... : - 10% SLE or
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... fibromyalgia) • Infections ... Malignancy (e.g. hematologic ... Seizures • Strokes Skin
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