23 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
anticoagulant dosing ... #DOAC #Bridging ... Anticoagulant #Anticoagulation ... #Rivaroxaban #Edoxaban ... #Pharmacology #Hematology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... if CrCl < 50) Edoxaban ... @Bloodman #DOAC ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Anticoagulants and DOACs ... Rivaroxaban, Apixaban, Edoxaban ... , Betrixaban, DOAC ... #anticoagulation ... #Switching #hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... for appropriate dosing ... #DOAC #VTE #Malignancy ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Betrixaban (Bevyxxa), Edoxaban ... PCC (Kcentra) #anticoagulation ... #doac #noac #pharmacology ... #hematology #reversal
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
**Edoxaban is initiated ... bleeding risk during ... #DOAC #VTE #Malignancy ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology
Recurrent / Breakthrough DVT During Anticoagulation

Subtherapeutic Anticoagulation
Hypercoagulable State 
 - Antithrombin deficiency 
 - Hypercoagulability ot
Breakthrough DVT During ... Anticoagulation ... - Behcet's disease ... Recurrent #DVT #VTE ... #hematology #differential
Venous Thromboembolism Treatment Algorithm
Branch points: 
Active bleeding?  Active malignancy? Provoked?

- Dr. Joseph Shatzel
@Clotmaster

#Management #VTE #DVT
Thromboembolism Treatment ... #Management #VTE ... Thromboembolism #Treatment ... #Hematology #Anticoagulation
Algorithm for the Long-Term Treatment of Venous Thromboembolism 

Reference: https://doi.org/10.1182/blood.2019002364

by Dr. Clive Kearon and Dr. Susan
the Long-Term Treatment ... #LongTerm #Treatment ... Thromboembolism #VTE ... #Anticoagulation ... #Algorithm #Hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... Edoxaban, rivaroxaban ... pathway whereas edoxaban ... Chemotherapy #Oncology #Hematology