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diagnosis differential management algorithm causes anemia lfts syndrome transaminitis gastroenterology injury acute ascites comparison nonalcoholic pbc primary alcoholic biliary hbv
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
100-500): • NAFLD ... • Cirrhosis ... Chronic Viral Hepatitis ... • Acute Viral Hepatitis ... Differential #Diagnosis #hepatology
NAFLD / NASH Progression Timeline Healthy Liver → NAFLD/NASH → 0.25-3.2%/year → Cirrhotic NASH → 0.3-2.6%/year →
Timeline Healthy Liver ... 0.25-3.2%/year → Cirrhotic ... /NASH → Cirrhotic ... Dietary habits • Cirrhotic ... Progression #Timeline #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Cholestatic disease ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Etiologies of Cirrhosis ... Inflammation - Hepatitis ... 15 percent) - Hepatitis ... Nonalcoholic fatty liver ... #Differential #Hepatology
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 Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... months without treatment ... disease, liver ... #Failure #Cirrhosis ... #Hepatology #gastroenterology
Signs of Chronic Liver Disease ( Cirrhosis ) #Diagnosis #Cirrhosis #Signs #Symptoms #Hepatology
Signs of Chronic Liver ... Disease ( Cirrhosis ... #Diagnosis #Cirrhosis ... Signs #Symptoms #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Hemochromatosis, Wilson's Disease ... Antitrypsin • Other: NAFLD ... Syndrome, Celiac Disease ... , Infiltrative Disease ... Acute #algorithm #hepatology
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Diagnosis Chronic liver ... disease (cirrhosis ... or chronic hepatitis ... failure - 3-5% Cirrhosis ... Differential #Diagnosis #hepatology
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary ... Biliary Cirrhosis ... pathophysiology #pbc #psc #hepatology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
of Severe Acute Liver ... Injury - Ichemic hepatitis ... - Drug-Induced liver ... - Wilson disease ... #Differential #Hepatology
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