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diagnosis biliary pbc algorithm differential management syndrome alkaline alp calling chemistry cholangitis consultation gastroenterology giconsult hepatitis hepatopulmonary hps hyophosphatasia injury
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... Elevated ALP 2. ... Liver biopsy findings ... Diagnosis #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
/Liver failure ... obstruction • ALP ... or higher • Liver ... cholangitis #diagnosis #workup ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
of cholestatic disease ... disease: > 2 ... hepatitis: < 1 • Cirrhosis ... Bilirubin: RBC (hemolysis ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
hepatitis: < 1 • Cirrhosis ... Gilbert's syndrome • Hemolysis ... Bilirubin: RBC (hemolysis ... LDH: Heart, RBC (hemolysis ... diagnosis #algorithm #hepatology
The Liver Consult Primer - Guide to calling a consult HPI: - Start with reason for consult
Primer - Guide ... Gl History - Cirrhosis ... disease work up ... Consultation #GIConsult #Primer ... Calling #Referral #Hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver ... Malnutrition • Wilson's disease ... Pernicious anemia/B12 ... • Elevation of urinary ... Hyophosphatasia #hepatology
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... line therapy if ALP ... Stage & survey disease ... #Management #Treatment ... #hepatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
vasculitis: 10%-16% Liver ... biliary cirrhosis ... Nephrogenic DI Hematologic ... Cryoglobulinemia (4%-12% ... Adenocarcinoma Treatment
Hepatopulmonary Syndrome - Illness Script HPS is a pulmonary disorder of chronic liver disease characterized by a
• Stigmata of cirrhosis ... the left heart TREATMENT ... mortality rate of ~12% ... only definitive treatment ... #diagnosis #hepatology
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