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diagnosis differential mds myelodysplastic neurology algorithm aplastic b1 ckd cobalamin encephalopathy hemodialysis myelitis myelodysplasia pancytopenia pruritus syndromes thiamine transverse uremia
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management Diagnosis - Caine Criteria (2 of
Diagnosis and Management ... development of Korsakoff syndrome ... (chronic B1 deficiency ... #Diagnosis #Management ... #neurology #nutrition
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
• Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis Nutritional ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... only curative treatment ... #treatment #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
, GATA2 deficiency ... , CTLA4 deficiency ... Treatment: ... #oncology #hematology ... #diagnosis #management
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... Check for IF ab Treatment ... #Cobalamin #Deficiency ... #diagnosis #management ... #nutrition
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Platelet Disorders • Nutritional ... : vitamin B12 or ... • Copper deficiency ... #diagnosis #hematology ... #oncology
Etiologies of Vitamin B12 Deficiency • Inadequate intake - Rare but seen in very strict vegans
autoantibodies (pernicious anemia ... insufficiency, blind loops syndromes ... malabsorption syndromes ... differential #diagnosis #hematology ... #nutrition
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
antibodies • Nutritional ... Deficiency: - ... Vitamin B12, E, ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management
Management of Pruritus in Patients with Chronic Kidney Disease Pruritus with no primary lesions - differential diagnosis:
pruritus • Hematologic ... pruritus (Iron deficiency ... anemia, Polycythemia ... #Pruritus #Treatment ... #Management #Nephrology
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